USA v Paraguay betting picks and prediction
The United States begin their 2026 FIFA World Cup campaign on Saturday when they face Paraguay at SoFi Stadium in Los Angeles in the opening match of Group D.
The Americans enter the tournament carrying significant expectations as co-hosts, with Mauricio Pochettino’s side aiming to make a deep run on home soil. Paraguay arrive as dangerous underdogs, however, and have already shown throughout qualifying that they are capable of frustrating more fancied opponents.
The USA is priced at 1.95 to defeat Paraguay (4.00), while the draw is paying 3.30 with betting sites. Christian Pulisic heads the goalscoring markets after establishing himself as the focal point of the American attack over the past decade.
The importance of a positive start cannot be understated. The United States have progressed from the group stage in each of their last six World Cups when avoiding defeat in their opener, while all four of their group-stage eliminations have followed an opening-match loss.
The pressure of playing at home also should not be underestimated. If Paraguay scores early it will silence the sellout crowd and the 1-0 scoreline will feel like a mountain to climb.
Group D at the World Cup also contains Australia and Türkiye, with the United States the top-ranked nation in the section and favourites with football betting sites to progress to the knockout stage.
Below we will run you through the latest US and Paraguay team news, present our free tips and give you our match prediction. We can’t wait for this one!

USA team news
The United States enter the tournament buoyed by strong support and growing optimism surrounding a talented squad that is reaching its prime years together.
Although the Americans suffered a 2-1 friendly defeat to Germany in Chicago recently, Antonee Robinson’s spectacular goal provided a reminder of the attacking quality available to Pochettino. More importantly, the atmosphere generated by over 60,000 supporters offered a glimpse of the backing the hosts can expect throughout the tournament.
Former US captain John Harkes believes the current squad is capable of making a deep run if it can stay healthy and handle the pressure of a home World Cup. Harkes pointed to the growing number of players competing in Europe’s major leagues as a key advantage for the Americans.
Christian Pulisic remains the headline act after earning more than 80 international caps and establishing himself as one of the most productive players in national team history. He will be supported by Monaco striker Folarin Balogun, Juventus midfielder Weston McKennie and Bournemouth captain Tyler Adams.
There are some concerns at the back. Chris Richards has been managing an ankle issue and remains in doubt, meaning Tim Ream could again be asked to marshal the defence alongside Miles Robinson.
The United States are paying 51.00 to win the World Cup with international betting sites, reflecting growing confidence that the hosts can challenge the world’s leading nations.
Paraguay team news
Paraguay arrive at the World Cup as one of South America’s most disciplined and defensively organised teams, but they have suffered a major setback ahead of their opening match.
Julio Enciso sustained a right thigh injury during a recent friendly victory over Nicaragua and is expected to miss Paraguay’s opening two group matches. The Brighton attacker was one of the side’s most influential players during qualifying and his absence removes a significant source of creativity.
Without Enciso, much of the attacking responsibility falls on former Newcastle United star Miguel Almirón and talented midfielder Diego Gómez. The pair will be tasked with creating opportunities for strikers Alex Arce and Antonio Sanabria.
Paraguay’s defensive structure remains their biggest strength. Gustavo Gómez, Omar Alderete and Junior Alonso form an experienced defensive core that has consistently made life difficult for opposition forwards.
The South Americans will also take confidence from their recent improvement on the international stage, although they were beaten 2-1 by the United States in a friendly meeting between the nations last November.
Their outsider status is reflected by World Cup odds of 251.00, but Paraguay have built their reputation on proving difficult to break down and could pose problems for the hosts if allowed to settle into the contest.
USA vs Paraguay odds
Match Result
- USA1.95
- Draw3.30
- Paraguay4.00
Both Teams To Score
- Yes2.00
- No1.73
To Win Both Halves
- USA5.75
- Paraguay15.00
- Neither1.17
World Cup Winner
- USA51.00
- Paraguay251.00
USA vs Paraguay betting tips
WGL’s football betting expert has analysed the numbers and found a pair of betting angles worth considering for the Group D opener. Here are our free World Cup USA v Paraguay picks:
Christian Pulisic to score anytime
Pulisic has built a reputation as the USA’s most reliable attacking weapon and remains the player most likely to produce a decisive moment in front of goal. The AC Milan star has scored more than 30 international goals and has consistently delivered in World Cup qualifying, CONCACAF Nations League matches, Gold Cups and friendlies. He remains heavily involved in set pieces, frequently attacks from dangerous central areas and carries the responsibility of leading the American attack. With the hosts expected to enjoy more possession and create the better chances, Pulisic looks well placed to add to his international tally in what should be an emotionally charged World Cup opener. He is paying around 3.00 to score anytime with US gambling sites.
Under 2.5 total goals
One betting angle worth considering is Under 2.5 Total Goals. Paraguay are known for their disciplined defensive structure and regularly make matches difficult for opponents by limiting space and restricting clear-cut chances. While the USA should control possession for long periods, breaking down a compact South American defence is unlikely to be straightforward. International football also tends to be more tactical and cautious than club football, particularly during the opening stages of major tournaments when avoiding mistakes becomes a priority. Paraguay’s loss of Julio Enciso may further reduce their attacking threat, making scorelines such as 1-0, 2-0 or even 1-1 realistic outcomes.
USA vs Paraguay prediction
USA should edge Paraguay thanks to their greater attacking depth, pace in transition and home support. Paraguay are organised and rarely concede heavily, which suggests chances could come at a premium throughout the contest. The South Americans have also been weakened by the absence of Julio Enciso, placing extra pressure on Miguel Almirón and Diego Gómez to provide creativity. With Pulisic, Balogun and Robinson capable of producing decisive moments, the Americans look better equipped to break the deadlock. A tight contest is expected, but the USA should have enough quality to begin their World Cup campaign with three points. Our final USA v Paraguay prediction is a 1-0 or 2-0 victory for the hosts.



